PEP (post-exposure prophylaxis) can help prevent HIV after a possible exposure—but starting quickly matters. Learn when to seek care, how to take the 28-day course, possible side effects, and why follow-up HIV testing is essential. Think you may have been exposed to HIV? Don’t wait for symptoms. Contact a healthcare provider, urgent care, or an emergency department right away. PEP should begin as soon as possible, ideally within 24 hours and no later than 72 hours after exposure. This brief Rehealthify explainer covers how PEP helps stop HIV from establishing an infection, why completing treatment matters, and what to do if side effects such as nausea bother you. PEP is not a guarantee of protection, and follow-up testing remains essential. The video also explains the distinction between emergency PEP and asking about PrEP for ongoing HIV prevention. CHAPTERS 00:00 Possible HIV exposure: don’t wait for symptoms 00:11 When to start PEP and where to get help 00:28 The 28-day course and follow-up HIV testing 00:38 Side effects and PrEP for ongoing protection For more clear, evidence-based health information without the hype, subscribe to Rehealthify. Subscribe to Rehealthify Medical Disclaimer: This content is for educational and informational purposes only and is not medical advice. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare professional regarding your health, medications, and treatment decisions. Do not start, stop, change, or adjust medication based solely on this video. Rehealthify is an independent health-information and education channel. This video does not endorse a particular medication or guarantee an outcome. Sources & References • CDC — Preventing HIV with PEP https://www.cdc.gov/hiv/prevention/pep.html • CDC — Antiretroviral Postexposure Prophylaxis After Sexual, Injection Drug Use, or Other Nonoccupational Exposure to HIV: United States Recommendations, 2025 https://www.cdc.gov/mmwr/volumes/74/rr/rr7401a1.htm #pep #hivprevention #postexposureprophylaxis #rehealthify